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The total sample size was 140 participants, with thirty-five in each group. When it begins to interfere with oral hygiene, it can also lead to poor oral health outcomes. 2018;2018:110. p values of<0.05 were considered as statistically significant. Comparative efficacy of BioMin-F, Colgate Sensitive Pro-relief and Canines and premolars are the most commonly affected teeth among 2530% of the adult population [2]. Written informed consent was obtained with a signed agreement plan to visit for six weeks at interim efficacy intervals of day three, week two, week four, and week six. Google Scholar. Dentifrices were removed carefully after one minute of undisturbed application by rinsing the air lightly with an air syringe, and the subject was asked to spit. Venkataramana S, Jeyaraman SK, Kothimbakkam SSK, Chellathurai BNK. If symptoms persist, talk to your healthcare professional. In addition, one-Way ANOVA with Post Hoc Tukey for pair-wise comparison was used to compare treatment groups computing percent change from baseline with formula (post-application mean scores-baseline mean scores/baseline mean scores). Besides, these findings of the current study could be related to previously conducted clinical trials indicating the better clinical effectiveness of Pro-argin than strontium acetate against air-blast and tactile stimulus after three days and one week of application [30, 31]. [32] reported statistically significant improvement in mechanical stimulated DH with Pro-argin immediately after topical application relative to 8% strontium Acetate in 2016. Grading of Recommendations, Assessment, Development and Evaluations. Part of Individuals either with dental caries, heavily restored, or cracked teeth, or with orthodontic or prosthetic appliances, or with localised or generalised gingivitis or pulpitis and heavy calculus or using any desensitising toothpaste or mouth wash or any other desensitising products up to six weeks before the study were excluded from this trial. [16] in a systematic review in 2015. Results of our study, together with the results of the previous studies, confirm the immediate clinical efficacy of Pro-argin for the relief of DH. The datasets analysed during the current study are available from the corresponding author on reasonable request. Click & Collect. Desensitizing toothpastes for dentin hypersensitivity: a network meta-analysis. The statistically significant change in mean scores of DH was observed with FCPS with p<0.05 relative to baseline for sustained relief from DH at follow-ups on day 3, week 2, week 4, and week 6, using clinical parameters of SCASS and VAS. * For instant relief, apply directly to the sensitive tooth with finger tip and gently massage for 1 minute. Based on the outcomes of previous systematic reviews and meta-analysis, the rationale of the present study was to substantiate the claim of immediate pain relief after one-minute application in DH by non-invasive surface application of OTC dentifrices containing Pro-arginin Colgate Sensitive Pro-Relief, and 8% strontium acetate in Sensodyne Rapid Action and other objective was the comparative evaluation of the clinical efficacy of three technologies, BAG-based FCPS in BioMinR F, Pro-argin, and 8% strontium acetate at efficacy intervals of day three, week two, four and six for sustained inhibition of painful stimulus provoking DH as all three are dentinal tubular occluding dentifrices. 2018;9(3):3306. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. Clinical Efficacy Of BioMin F, Colgate Sensitive Pro-Relief And Benefits: Colgate Sensitive Prevent and Repair is clinically proven to provide superior relief vs Sensodyne Extra Whitening at 8 weeks1 Long-lasting relief from hypersensitivity with continued use Superior sensitivity relief at 8 weeks vs the leading Sensodyne toothpaste variant 1 Hu ML, Zheng G, Lin H, Yang M, Zhang YD, Han JM. In this way, variability in individuals' pain response was tried to be controlled and will be discussed in part 2 of this manuscript. These commercially available tooth paste are one n the same thing.Both says they work in reducing the tooth senstivity due to cold intake.These may help olny during the early stages but when there is sensation to both cold and hot drinks and pain, you need to visit a dentist. The secondary objective of the study was to compare the clinical efficacy of Pro-argin, strontium acetate, and FCPS for immediate and sustained treatment response in DH that was measured on SCASS as a primary outcome measure and VAS as secondary outcome measure at efficacy intervals of one minute, day-three, week two, four and six. The study's primary objective was to investigate pain relief in one minute with Pro-argin and strontium acetate in DH measured on SCASS as a primary outcome measure and VAS as a secondary outcome measure. Follow the directions for use. Dentine hypersensitivity. Pashley D. Consensus-based recommendations for the diagnosis and management of dentin hypersensitivity. and Ayad et al. 2010;11:32. In our study, Pro-argin treatment revealed an immediate clinical reduction of 45.7% on SCASS, 56% on VAS used for mechanical stimuli, and 48.1% on VAS used for water jet stimuli in DH demonstrated in Tables 3, 5, and 6. Compared to stannous fluoride/sodium fluoride and novamin/sodium fluoride. IRB-1351/DUHS/Approval/2019/184. Comparative evaluation of desensitizing efficacy of dentifrice containing 5% fluoro calcium phosphosilicate versus 5% calcium sodium phosphosilicate: a randomized controlled clinical trial. Therefore, the first null hypothesis was that mean scores for pain due to DH among different treatment groups for immediate relief remain. Docimo R et al. Based on the synthesis of study results, we can conclude that Pro-argin in Colgate Sensitive Pro-relief and 8% strontium acetate in Sensodyne Rapid Action both are effective for pain relief in one minute after application in DH with better immediate treatment response of Pro-argin than strontium acetate. SEALS & REPAIRS: Pro-Argin technology helps to seal and repair the sensitive areas of teeth. In addition, they were responding to air-blast stimulus on the Schiff cold air sensitivity scale (SCASS) with scores2 [22]. observed a significantly greater reduction in sensitivity from air and tactile stimuli when compared to a potassium ion toothpaste, an effect sustained at two, four and eight weeks of use. The findings agreed with another in vitro trial by Mahmoodi et al. These then interact to form a complex with positive charge. J Dent. Benefits. According to Holland's guidelines of conducting a trial for managing DH, two diagnostic tools are sufficient for quantitative assessment of the clinical efficacy of desensitisers. Was this answer helpful? 2020;12(2):87. The comparative evaluation was done for the clinical efficacy of Pro-argin and 8% strontium acetate, and a statistically significant (p>0.05) difference was not found between these two formulations in the current study. In our study, patient compliance related to the recommended time of application and method of the application provided by doctors was controlled by subjecting multiple efficacy intervals and different methods for assessment of the change in pain scores due to DH. Dentin hypersensitivity treatments work in one of two ways. 2017;30(4):2216. Colgate SENSITIVE INSTANT Relief Repair & Prevent Colgate SENSITIVE INSTANT Relief Repair & Prevent toothpaste provides instant* and long-lasting sensitivity relief and lasting gum protection: PRO-ARGIN Technology repairs sensitive areas of the teeth for instant and long-lasting pain relief1,2, Zinc helps to strengthen gums and to prevent recession a key cause of sensitivity3. This clinical trial was not funded by any agency in public, commercial or not-for-profit sectors. 2009;22:3A-7A. We provided oral hygiene instructions and ways of relieving their pain from DH to improve their quality of life. All rights reserved. Manage cookies/Do not sell my data we use in the preference centre. A meta-analysis by Grnberg et al. Toothpaste | Dental Products | Colgate Professional Mockdeci H, Polonini H, Martins I, Granato A-P, Raposo N. Evaluation of ex vivo effectiveness of commercial desensitizing dentifrices. Colgate Sensitive Instant Relief Toothpaste, 6 x 75ml | C - Costco Another study by Hines et al. All the treatment groups subjected to testing in the present study revealed a considerable clinically significant symptomatic reduction in DH relative to the pre-treatment condition that was also statistically significant. Modified bass brushing method was demonstrated on the same model before the first application of dentifrices in the dental clinic. Pessoa, Loretto et al. Explore the videos and articles found on this page to assist in better oral care. J Clin Dent 2009; 20 (Spec Iss): 123-130. Colgate-Palmolive Company 2018. YYYY Colgate-Palmolive Company. 4.2 5 0 221 221 Colgate Sensitive Pro-Relief Enamel Rebuild toothpaste helps instantly repair sensitive teeth and provides lasting protection against hypersensitivity. Plain bi-carb soda and coconut butter do a far better job at cleaning and desensitising. Colgate-Palmolive Company 2018. Dentifrices-containing Pro-argin showed a significant reduction in DH with mean scores of (4.201.70) followed by strontium acetate (4.651.87) followed by FCPS (5.101.88) one minute after application. OTC dentifrices with Pro-argin and strontium acetate are effective for immediate pain relief from DH, and FCPS could be the best possible treatment option for long term management of DH. Free postage. After six weeks, Pro-argin-based dentifrices showed greater clinical efficacy with mean scores (2.151.92) than other treatment arms for mechanical stimulated DH. statement and Colgate Sensitive Instant Repair & Prevent Toothpaste 75ml - Superdrug Shrimathi S. Effect of BiominF, NovaminR, Argin and nanohydroxy particles containing dentifrices on dentine hypersensitivity and gingivitis among 3544 years aged population of Madurai district: a randomized controlled trial (RCT). Colgate Sensitive Pro Relief Multi Protection, offering all of the above benefits in one convenient formula. Significantly greater sensitivity reduction with twice - daily brushing compared to control toothpaste with potassium ions. Comparative efficacy of BioMin-F, Colgate Sensitive Pro-relief and Sensodyne Rapid Action in relieving dentin hypersensitivity: a randomized controlled trial. Felix J, Ouanounou A. Dentin hypersensitivity: etiology, diagnosis, and management. Then, the repeated measure was obtained after five minutes for previous pain recovery, and dentifrices were provided to the patient for self-application. Researchers have investigated the clinical efficacy of popular propriety occluding dentifrices containing Pro-argin, strontium acetate, and FCPS formulations for treating DH and have found no adverse effects. Vu Pham T, Anh Nguyen T. Clinical evaluation of the desensitizing efficacy of a paste containing 8% arginine and calcium carbonate. compared Colgate Sensitive Pro Relief to another leading brand that desensitizes with a 2% potassium ion formula. This toothpaste prevents sensitivity coming back by building a protective barrier that acts like . PubMed Central Thus, 128 participants completed the trial and were statistically analyzed for primary outcome measure of SCASS scores after lost to follow up (Fig. J Dent. J Evid Based Dent Pract. Clinically proven lasting relief for 8 weeks. Colgate Sensitive Toothpaste - Colgate Professional For instant relief, just apply directly to the sensitive tooth with finger tip and gently massage for one minute. For instant relief, just apply directly to the sensitive tooth with finger tip and gently massage for one minute. SJAZ has contributed to the conception, design, interpretation of results and critically revised the manuscript. 2017;2017:2. Plus it has the freshness you trust from Colgate! Saba Arshad. 2017;2017:2. Colgate Sensitive Instant* Relief Enamel Repair tandkrm ger dig kliniskt bevisad lngvarig lindring** mot ilningar i tta veckor nr du anvnder den tv gnger om dagen. Int J Dent. A total of 128 participants completed the trial.